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In situ phosphorylation of the α subunit of eukaryotic initiation factor 2 in reticulocyte lysates inhibited by heme deficiency, double-stranded RNA, oxidized glutathione, or the heme-regulated protein kinase

Protein synthesis initiation in reticulocyte lysates is inhibited by heme deficiency, low levels of double-stranded RNA (dsRNA), oxidized glutathione (GSSG), or the purified kinase (HRI) that acts on the α polypeptide of eukaryotic initiation factor 2 (eIF-2α). The phosphoprotein profiles produced i...

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Detalhes bibliográficos
Main Authors: Ernst, Vivian, Levin, Daniel H., London, Irving M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC383548/
https://ncbi.nlm.nih.gov/pubmed/287050
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