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In situ phosphorylation of the α subunit of eukaryotic initiation factor 2 in reticulocyte lysates inhibited by heme deficiency, double-stranded RNA, oxidized glutathione, or the heme-regulated protein kinase

Protein synthesis initiation in reticulocyte lysates is inhibited by heme deficiency, low levels of double-stranded RNA (dsRNA), oxidized glutathione (GSSG), or the purified kinase (HRI) that acts on the α polypeptide of eukaryotic initiation factor 2 (eIF-2α). The phosphoprotein profiles produced i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ernst, Vivian, Levin, Daniel H., London, Irving M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1979
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC383548/
https://ncbi.nlm.nih.gov/pubmed/287050
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