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The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

Autophagy is a fundamental adaptive response to amino acid starvation orchestrated by conserved gene products, the autophagy (ATG) proteins. However, the cellular cues that activate the function of ATG proteins during amino acid starvation are incompletely understood. Here we show that two related s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Wei, Yongjie, An, Zhenyi, Zou, Zhongju, Sumpter, Rhea, Su, Minfei, Zang, Xiao, Sinha, Sangita, Gaestel, Matthias, Levine, Beth
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337728/
https://ncbi.nlm.nih.gov/pubmed/25693418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05289
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