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The Aberrant Gene-End Transcription Signal of the Matrix M Gene of Human Parainfluenza Virus Type 3 Downregulates Fusion F Protein Expression and the F-Specific Antibody Response In Vivo

Human parainfluenza virus type 3 (HPIV3), a paramyxovirus, is a major viral cause of severe lower respiratory tract disease in infants and children. The gene-end (GE) transcription signal of the HPIV3 matrix (M) protein gene is identical to those of the nucleoprotein and phosphoprotein genes except...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Lingemann, Matthias, Surman, Sonja, Amaro-Carambot, Emérito, Schaap-Nutt, Anne, Collins, Peter L., Munir, Shirin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337556/
https://ncbi.nlm.nih.gov/pubmed/25589643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03148-14
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