Conserved Motifs in a Tombusvirus Polymerase Modulate Genome Replication, Subgenomic Transcription, and Amplification of Defective Interfering RNAs

The replication of plus-strand RNA virus genomes is mediated by virally encoded RNA-dependent RNA polymerases (RdRps). We have investigated the role of the C-proximal region in the RdRp of tomato bushy stunt virus (TBSV) in mediating viral RNA synthesis. TBSV is the prototype species in the genus To...

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Vydáno v:J Virol
Hlavní autoři: Gunawardene, Chaminda D., Jaluba, Karolina, White, K. Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337532/
https://ncbi.nlm.nih.gov/pubmed/25568204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03378-14
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