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Inhibition of Sterol Biosynthesis Reduces Tombusvirus Replication in Yeast and Plants

The replication of plus-strand RNA viruses depends on subcellular membranes. Recent genome-wide screens have revealed that the sterol biosynthesis genes ERG25 and ERG4 affected the replication of Tomato bushy stunt virus (TBSV) in a yeast model host. To further our understanding of the role of stero...

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Autors principals: Sharma, Monika, Sasvari, Zsuzsanna, Nagy, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820916/
https://ncbi.nlm.nih.gov/pubmed/20015981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02003-09
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