Inhibition of phospholipid biosynthesis decreases the activity of the tombusvirus replicase and alters the subcellular localization of replication proteins

Replication of plus-strand RNA viruses depends on lipids present in cellular membranes. Recent genome-wide screens have revealed that eight phospholipid biosynthesis genes affected the replication of Tomato bushy stunt virus (TBSV) in yeast model host. To test the importance of phospholipids in TBSV...

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Hlavní autoři: Sharma, Monika, Sasvari, Zsuzsanna, Nagy, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107895/
https://ncbi.nlm.nih.gov/pubmed/21561636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.04.008
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