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Conserved Motifs in a Tombusvirus Polymerase Modulate Genome Replication, Subgenomic Transcription, and Amplification of Defective Interfering RNAs

The replication of plus-strand RNA virus genomes is mediated by virally encoded RNA-dependent RNA polymerases (RdRps). We have investigated the role of the C-proximal region in the RdRp of tomato bushy stunt virus (TBSV) in mediating viral RNA synthesis. TBSV is the prototype species in the genus To...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Gunawardene, Chaminda D., Jaluba, Karolina, White, K. Andrew
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337532/
https://ncbi.nlm.nih.gov/pubmed/25568204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03378-14
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