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Serine Phosphorylation of the Hepatitis C Virus NS5A Protein Controls the Establishment of Replication Complexes

The hepatitis C virus (HCV) nonstructural 5A (NS5A) protein is highly phosphorylated and involved in both virus genome replication and virion assembly. We and others have identified serine 225 in NS5A to be a phosphorylation site, but the function of this posttranslational modification in the virus...

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Pubblicato in:J Virol
Autori principali: Ross-Thriepland, Douglas, Mankouri, Jamel, Harris, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337517/
https://ncbi.nlm.nih.gov/pubmed/25552726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02995-14
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