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Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions

Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is a phosphoprotein that plays key, yet poorly defined, roles in both virus genome replication and virion assembly/release. It has been proposed that differential phosphorylation could act as a switch to regulate the various functions of NS5A;...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Goonawardane, Niluka, Gebhardt, Anna, Bartlett, Christopher, Pichlmair, Andreas, Harris, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553161/
https://ncbi.nlm.nih.gov/pubmed/28615203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00805-17
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