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High-Throughput Screening of the Yeast Kinome: Identification of Human Serine/Threonine Protein Kinases That Phosphorylate the Hepatitis C Virus NS5A Protein

The hepatitis C virus NS5A protein plays a critical role in virus replication, conferring interferon resistance to the virus through perturbation of multiple intracellular signaling pathways. Since NS5A is a phosphoprotein, it is of considerable interest to understand the role of phosphorylation in...

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Detalhes bibliográficos
Main Authors: Coito, Carlos, Diamond, Deborah L., Neddermann, Petra, Korth, Marcus J., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371080/
https://ncbi.nlm.nih.gov/pubmed/15016873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3502-3513.2004
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