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Roles of the Phosphorylation of Specific Serines and Threonines in the NS1 Protein of Human Influenza A Viruses

We demonstrate that phosphorylation of the NS1 protein of a human influenza A virus occurs not only at the threonine (T) at position 215 but also at serines (Ss), specifically at positions 42 and 48. By generating recombinant influenza A/Udorn/72 (Ud) viruses that encode mutant NS1 proteins, we dete...

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Detalhes bibliográficos
Main Authors: Hsiang, Tien-Ying, Zhou, Ligang, Krug, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457261/
https://ncbi.nlm.nih.gov/pubmed/22787231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00732-12
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