Nuclear and Nucleolar Targeting of Influenza A Virus NS1 Protein: Striking Differences between Different Virus Subtypes

Influenza A virus nonstructural protein 1 (NS1A protein) is a virulence factor which is targeted into the nucleus. It is a multifunctional protein that inhibits host cell pre-mRNA processing and counteracts host cell antiviral responses. We show that the NS1A protein can interact with all six human...

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Detalhes bibliográficos
Main Authors: Melén, Krister, Kinnunen, Leena, Fagerlund, Riku, Ikonen, Niina, Twu, Karen Y., Krug, Robert M., Julkunen, Ilkka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900311/
https://ncbi.nlm.nih.gov/pubmed/17376915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01714-06
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