Truncated tau deregulates synaptic markers in rat model for human tauopathy

Synaptic failure and neurofibrillary degeneration are two major neuropathological substrates of cognitive dysfunction in Alzheimer’s disease (AD). Only a few studies have demonstrated a direct relationship between these two AD hallmarks. To investigate tau mediated synaptic injury we used rat model...

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Publicado en:Front Cell Neurosci
Autores principales: Jadhav, Santosh, Katina, Stanislav, Kovac, Andrej, Kazmerova, Zuzana, Novak, Michal, Zilka, Norbert
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337338/
https://ncbi.nlm.nih.gov/pubmed/25755633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00024
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