Genetic Background Influences the Propagation of Tau Pathology in Transgenic Rodent Models of Tauopathy

Alzheimer’s disease (AD), the most common tauopathy, is an age-dependent, progressive neurodegenerative disease. Epidemiological studies implicate the role of genetic background in the onset and progression of AD. Despite mutations in familial AD, several risk factors have been implicated in sporadi...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Smolek, Tomas, Cubinkova, Veronika, Brezovakova, Veronika, Valachova, Bernadeta, Szalay, Peter, Zilka, Norbert, Jadhav, Santosh
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917578/
https://ncbi.nlm.nih.gov/pubmed/31920624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00343
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