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Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens

Repeated exposure to ethanol followed by withdrawal leads to alterations in glutamatergic signaling and impaired synaptic plasticity in the nucleus accumbens (NAc) in both clinical and preclinical models of ethanol exposure. Homer2 is a member of a family of postsynaptic density (PSD) scaffolding pr...

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Pubblicato in:Front Pharmacol
Autori principali: McGuier, Natalie S., Padula, Audrey E., Mulholland, Patrick J., Chandler, L. Judson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337331/
https://ncbi.nlm.nih.gov/pubmed/25755642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00028
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