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Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens

Repeated exposure to ethanol followed by withdrawal leads to alterations in glutamatergic signaling and impaired synaptic plasticity in the nucleus accumbens (NAc) in both clinical and preclinical models of ethanol exposure. Homer2 is a member of a family of postsynaptic density (PSD) scaffolding pr...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: McGuier, Natalie S., Padula, Audrey E., Mulholland, Patrick J., Chandler, L. Judson
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337331/
https://ncbi.nlm.nih.gov/pubmed/25755642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00028
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