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Involvement of the GluN2A and GluN2B Subunits in Synaptic and Extrasynaptic N-methyl-d-aspartate Receptor Function and Neuronal Excitotoxicity

GluN2A and GluN2B are the major subunits of functional NMDA receptors (NMDAR). Previous studies have suggested that GluN2A and GluN2B may differentially mediate NMDAR function at synaptic and extrasynaptic locations and play opposing roles in excitotoxicity, such as neurodegeneration triggered by is...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhou, Xianju, Ding, Qi, Chen, Zhuoyou, Yun, Huifang, Wang, Hongbing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745357/
https://ncbi.nlm.nih.gov/pubmed/23839940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482000
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