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Shikonin Induces Apoptosis, Necrosis, and Premature Senescence of Human A549 Lung Cancer Cells through Upregulation of p53 Expression

Shikonin, a natural naphthoquinone pigment isolated from Lithospermum erythrorhizon, has been reported to suppress growth of various cancer cells. This study was aimed to investigate whether this chemical could also inhibit cell growth of lung cancer cells and, if so, works via what molecular mechan...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Yeh, Yueh-Chiao, Liu, Tsun-Jui, Lai, Hui-Chin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337265/
https://ncbi.nlm.nih.gov/pubmed/25737737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/620383
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