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Dynamics of CYP51: implications for function and inhibitor design
Sterol 14α-demethylase (cytochrome P450 family 51 (CYP51)) is an essential enzyme occurring in all biological kingdoms. In eukaryotes, it is located in the membrane of the endoplasmic reticulum. Selective inhibitors of trypanosomal CYP51s that do not affect the human CYP51 have been discovered in vi...
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| Publicado no: | J Mol Recognit |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337246/ https://ncbi.nlm.nih.gov/pubmed/25601796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.2412 |
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