Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension

BACKGROUND: Despite the availability of several antihypertensive medications, the morbidity and mortality caused by hypertension is on the rise, suggesting the need for investigation of novel signaling pathways involved in its pathogenesis. Recent evidence suggests the role of toll-like receptor (TL...

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Publicat a:J Neuroinflammation
Autors principals: Dange, Rahul B, Agarwal, Deepmala, Teruyama, Ryoichi, Francis, Joseph
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337244/
https://ncbi.nlm.nih.gov/pubmed/25879545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0242-7
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