Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension

BACKGROUND: Despite the availability of several antihypertensive medications, the morbidity and mortality caused by hypertension is on the rise, suggesting the need for investigation of novel signaling pathways involved in its pathogenesis. Recent evidence suggests the role of toll-like receptor (TL...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Dange, Rahul B, Agarwal, Deepmala, Teruyama, Ryoichi, Francis, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337244/
https://ncbi.nlm.nih.gov/pubmed/25879545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0242-7
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