Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension

BACKGROUND: Despite the availability of several antihypertensive medications, the morbidity and mortality caused by hypertension is on the rise, suggesting the need for investigation of novel signaling pathways involved in its pathogenesis. Recent evidence suggests the role of toll-like receptor (TL...

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Publicado en:J Neuroinflammation
Main Authors: Dange, Rahul B, Agarwal, Deepmala, Teruyama, Ryoichi, Francis, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337244/
https://ncbi.nlm.nih.gov/pubmed/25879545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0242-7
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