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The Mechanisms of RNA SHAPE Chemistry
The biological functions of RNA are ultimately governed by the local environment at each nucleotide. Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE) chemistry is a powerful approach for measuring nucleotide structure and dynamics in diverse biological environments. SHAPE reagent...
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| Published in: | J Am Chem Soc |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337229/ https://ncbi.nlm.nih.gov/pubmed/22475022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2104075 |
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