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The Mechanisms of RNA SHAPE Chemistry

The biological functions of RNA are ultimately governed by the local environment at each nucleotide. Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE) chemistry is a powerful approach for measuring nucleotide structure and dynamics in diverse biological environments. SHAPE reagent...

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Pubblicato in:J Am Chem Soc
Autori principali: McGinnis, Jennifer L., Dunkle, Jack A., Cate, Jamie H. D., Weeks, Kevin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337229/
https://ncbi.nlm.nih.gov/pubmed/22475022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2104075
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