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Identification of Chloramphenicol-Binding Protein in Escherichia coli Ribosomes by Affinity Labeling
Monoiodoamphenicol, a synthetic analogue of chloramphenicol, has been shown by competition experiments with chloramphenicol and lincomycin to bind at the same site of 70S ribosomes as chloramphenicol. At — 2° it forms a 1:1 complex with 70S ribosomes having a value of K (7.5 × 10(4) M(-1)) that is o...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1973
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4599619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.8.2229 |
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