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Identification of Chloramphenicol-Binding Protein in Escherichia coli Ribosomes by Affinity Labeling

Monoiodoamphenicol, a synthetic analogue of chloramphenicol, has been shown by competition experiments with chloramphenicol and lincomycin to bind at the same site of 70S ribosomes as chloramphenicol. At — 2° it forms a 1:1 complex with 70S ribosomes having a value of K (7.5 × 10(4) M(-1)) that is o...

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Hlavní autoři: Pongs, Olaf, Bald, Rolf, Erdmann, Volker A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1973
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC433707/
https://ncbi.nlm.nih.gov/pubmed/4599619
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