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HIF-1α Regulates Bone Formation after Osteogenic Mechanical Loading

HIF-1 is a transcription factor typically associated with angiogenic gene transcription under hypoxic conditions. In this study, mice with HIF-1α deleted in the osteoblast lineage (ΔHIF-1α) were subjected to damaging or non-damaging mechanical loading known to produce woven or lamellar bone, respect...

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Podrobná bibliografie
Vydáno v:Bone
Hlavní autoři: Tomlinson, Ryan E., Silva, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336830/
https://ncbi.nlm.nih.gov/pubmed/25541207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.12.015
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