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Acceleration of the Rate of Deamidation of GlyArgAsnArgGly and of Human Transferrin by Addition of l-Ascorbic Acid

Experiments on the model peptide, GlyArgAsnArgGly, and the protein, human transferrin, have shown that hydrolytic deamidation of these molecules is markedly accelerated by addition of physiologically significant concentrations of l-ascorbic acid. Since hydrolytic demidation has been suggested as an...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Robinson, Arthur B., Irving, Karen, McCrea, Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1973
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4516209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.7.2122
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