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Acceleration of the Rate of Deamidation of GlyArgAsnArgGly and of Human Transferrin by Addition of l-Ascorbic Acid

Experiments on the model peptide, GlyArgAsnArgGly, and the protein, human transferrin, have shown that hydrolytic deamidation of these molecules is markedly accelerated by addition of physiologically significant concentrations of l-ascorbic acid. Since hydrolytic demidation has been suggested as an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Robinson, Arthur B., Irving, Karen, McCrea, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4516209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.7.2122
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