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Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing
We describe an approach for targeted genome resequencing, called oligonucleotide-selective sequencing (OS-Seq), in which we modify the immobilized lawn of oligonucleotide primers of a next-generation DNA sequencer to function as both a capture and sequencing substrate. We apply OS-Seq to resequence...
में बचाया:
| में प्रकाशित: | Nat Biotechnol |
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| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336783/ https://ncbi.nlm.nih.gov/pubmed/22020387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1996 |
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