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Inflammation contributes to NKX3.1 loss and augments DNA damage but does not alter the DNA damage response via increased SIRT1 expression

The oxidative stress response is a cellular defense mechanism that protects cells from oxidative damage and cancer development. The exact molecular mechanism by which reactive oxygen species (ROS) contribute to DNA damage and increase genome instability in prostate cancer merits further investigatio...

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Publicat a:J Inflamm (Lond)
Autors principals: Debelec-Butuner, Bilge, Ertunc, Nursah, Korkmaz, Kemal Sami
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336697/
https://ncbi.nlm.nih.gov/pubmed/25705129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0057-4
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