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TNFα-Mediated Loss of β-Catenin/E-Cadherin Association and Subsequent Increase in Cell Migration Is Partially Restored by NKX3.1 Expression in Prostate Cells

Inflammation-induced carcinogenesis is associated with increased proliferation and migration/invasion of various types of tumor cells. In this study, altered β-catenin signaling upon TNFα exposure, and relation to loss of function of the tumor suppressor NKX3.1 was examined in prostate cancer cells....

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Autors principals: Debelec-Butuner, Bilge, Alapinar, Cansu, Ertunc, Nursah, Gonen-Korkmaz, Ceren, Yörükoğlu, Kutsal, Korkmaz, Kemal Sami
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215977/
https://ncbi.nlm.nih.gov/pubmed/25360740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109868
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