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Inflammation contributes to NKX3.1 loss and augments DNA damage but does not alter the DNA damage response via increased SIRT1 expression

The oxidative stress response is a cellular defense mechanism that protects cells from oxidative damage and cancer development. The exact molecular mechanism by which reactive oxygen species (ROS) contribute to DNA damage and increase genome instability in prostate cancer merits further investigatio...

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Detalhes bibliográficos
Publicado no:J Inflamm (Lond)
Main Authors: Debelec-Butuner, Bilge, Ertunc, Nursah, Korkmaz, Kemal Sami
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336697/
https://ncbi.nlm.nih.gov/pubmed/25705129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0057-4
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