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Cocaine Induces Nuclear Export and Degradation of Neuronal Retinoid X Receptor-γ via a TNF-α/JNK-Mediated Mechanism

Cocaine abuse represents an immense societal health and economic burden for which no effective treatment currently exists. Among the numerous intracellular signaling cascades impacted by exposure to cocaine, increased and aberrant production of pro-inflammatory cytokines in the CNS has been observed...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Kovalevich, Jane, Yen, William, Ozdemir, Ahmet, Langford, Dianne
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336643/
https://ncbi.nlm.nih.gov/pubmed/25586717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9573-x
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