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Cocaine-Induced Loss of White Matter Proteins in the Adult Mouse Nucleus Accumbens Is Attenuated by Administration of a β-Lactam Antibiotic during Cocaine Withdrawal

We report significantly decreased white matter protein levels in the nucleus accumbens in an adult mouse model of chronic cocaine abuse. Previous studies from human cocaine abuse patients show disruption of white matter and myelin loss, thus supporting our observations. Understanding the neuropathol...

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Main Authors: Kovalevich, Jane, Corley, Gladys, Yen, William, Rawls, Scott M., Langford, Dianne
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509758/
https://ncbi.nlm.nih.gov/pubmed/23031254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.08.013
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