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Cocaine Induces Nuclear Export and Degradation of Neuronal Retinoid X Receptor-γ via a TNF-α/JNK-Mediated Mechanism

Cocaine abuse represents an immense societal health and economic burden for which no effective treatment currently exists. Among the numerous intracellular signaling cascades impacted by exposure to cocaine, increased and aberrant production of pro-inflammatory cytokines in the CNS has been observed...

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Veröffentlicht in:J Neuroimmune Pharmacol
Hauptverfasser: Kovalevich, Jane, Yen, William, Ozdemir, Ahmet, Langford, Dianne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336643/
https://ncbi.nlm.nih.gov/pubmed/25586717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9573-x
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