Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp

The nucleotide (p)ppGpp mediates bacterial stress responses, but its targets and underlying mechanisms of action vary among bacterial species and remain incompletely understood. Here we characterize the molecular interaction between (p)ppGpp and guanylate kinase (GMK) revealing the importance of thi...

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Veröffentlicht in:Mol Cell
Hauptverfasser: Liu, Kuanqing, Myers, Angela R., Pisithkul, Tippapha, Claas, Kathy R., Satyshur, Kenneth A., Amador-Noguez, Daniel, Keck, James L., Wang, Jue D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336630/
https://ncbi.nlm.nih.gov/pubmed/25661490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.037
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