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Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp

The nucleotide (p)ppGpp mediates bacterial stress responses, but its targets and underlying mechanisms of action vary among bacterial species and remain incompletely understood. Here we characterize the molecular interaction between (p)ppGpp and guanylate kinase (GMK) revealing the importance of thi...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Liu, Kuanqing, Myers, Angela R., Pisithkul, Tippapha, Claas, Kathy R., Satyshur, Kenneth A., Amador-Noguez, Daniel, Keck, James L., Wang, Jue D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336630/
https://ncbi.nlm.nih.gov/pubmed/25661490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.037
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