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Randomized, Placebo-controlled Trial of Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis: The ACROSS Trial
OBJECTIVE: This trial evaluated the efficacy of acetaminophen in reducing oxidative injury, as measured by plasma F(2)-Isoprostanes, in adult patients with severe sepsis and detectable plasma cell-free hemoglobin. DESIGN: Single center, randomized, double-blind, placebo controlled phase II trial. SE...
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| Udgivet i: | Crit Care Med |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336619/ https://ncbi.nlm.nih.gov/pubmed/25474535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000000718 |
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