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The SIX1-EYA transcriptional complex as a therapeutic target in cancer

INTRODUCTION: The SIX homeodomain proteins and the EYA family of co-activators form a bipartite transcription factor complex that promotes the proliferation and survival of progenitor cells during organogenesis and is down-regulated in most adult tissues. Abnormal over-expression of SIX1 and EYA in...

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Publicat a:Expert Opin Ther Targets
Autors principals: Blevins, Melanie A, Towers, Christina Garlington, Patrick, Aaron N., Zhao, Rui, Ford, Heide L.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336540/
https://ncbi.nlm.nih.gov/pubmed/25555392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2014.978860
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