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A Novel Explanation for Observed CaMKII Dynamics in Dendritic Spines with Added EGTA or BAPTA
We present a simplified reaction network in a single well-mixed volume that captures the general features of CaMKII dynamics observed during both synaptic input and spine depolarization. Our model can also account for the greater-than-control CaMKII activation observed with added EGTA during depolar...
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| izdano v: | Biophys J |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336359/ https://ncbi.nlm.nih.gov/pubmed/25692602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.044 |
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