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The impacts of geometry and binding on CaMKII diffusion and retention in dendritic spines
We used a particle-based Monte Carlo simulation to dissect the regulatory mechanism of molecular translocation of CaMKII, a key regulator of neuronal synaptic function. Geometry was based upon measurements from EM reconstructions of dendrites in CA1 hippocampal pyramidal neurons. Three types of simu...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617044/ https://ncbi.nlm.nih.gov/pubmed/21104309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10827-010-0293-9 |
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