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A Novel Explanation for Observed CaMKII Dynamics in Dendritic Spines with Added EGTA or BAPTA

We present a simplified reaction network in a single well-mixed volume that captures the general features of CaMKII dynamics observed during both synaptic input and spine depolarization. Our model can also account for the greater-than-control CaMKII activation observed with added EGTA during depolar...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Matolcsi, Matt, Giordano, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336359/
https://ncbi.nlm.nih.gov/pubmed/25692602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.044
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