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Activation of NOTCH1 or NOTCH3 Signaling Skews Human Airway Basal Cell Differentiation toward a Secretory Pathway

Airway basal cells (BC) function as stem/progenitor cells capable of differentiating into the luminal ciliated and secretory cells to replenish the airway epithelium during physiological turnover and repair. The objective of this study was to define the role of Notch signaling in regulating human ai...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Gomi, Kazunori, Arbelaez, Vanessa, Crystal, Ronald G., Walters, Matthew S.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336283/
https://ncbi.nlm.nih.gov/pubmed/25700162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116507
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