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Alkylphosphocholine Analogs for Broad-Spectrum Cancer Imaging and Therapy
Many solid tumors contain an overabundance of phospholipid ethers relative to normal cells. Capitalizing on this difference, we created cancer-targeted alkylphosphocholine (APC) analogs through structure-activity analyses. Depending on the iodine isotope used, radioiodinated APC analog CLR1404 was u...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336181/ https://ncbi.nlm.nih.gov/pubmed/24920661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007646 |
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