Alkylphosphocholine Analogs for Broad-Spectrum Cancer Imaging and Therapy

Many solid tumors contain an overabundance of phospholipid ethers relative to normal cells. Capitalizing on this difference, we created cancer-targeted alkylphosphocholine (APC) analogs through structure-activity analyses. Depending on the iodine isotope used, radioiodinated APC analog CLR1404 was u...

詳細記述

保存先:
書誌詳細
出版年:Sci Transl Med
主要な著者: Weichert, Jamey P., Clark, Paul A., Kandela, Irawati K., Vaccaro, Abram M., Clarke, William, Longino, Marc A., Pinchuk, Anatoly N., Farhoud, Mohammed, Swanson, Kyle I., Floberg, John M., Grudzinski, Joseph, Titz, Benjamin, Traynor, Anne M., Chen, Hong-En, Hall, Lance T., Pazoles, Christopher J., Pickhardt, Perry J., Kuo, John S.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336181/
https://ncbi.nlm.nih.gov/pubmed/24920661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007646
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