AmgRS-mediated envelope stress-inducible expression of the mexXY multidrug efflux operon of Pseudomonas aeruginosa

AmgRS is an envelope stress-responsive two-component system and aminoglycoside resistance determinant in Pseudomonas aeruginosa that is proposed to protect cells from membrane damage caused by aminoglycoside-generated mistranslated polypeptides. Consistent with this, a ΔamgR strain showed increased...

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Publicat a:Microbiologyopen
Autors principals: Lau, Calvin Ho-Fung, Krahn, Thomas, Gilmour, Christie, Mullen, Erin, Poole, Keith
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335980/
https://ncbi.nlm.nih.gov/pubmed/25450797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.226
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