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Aminoglycoside-inducible expression of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: Involvement of the envelope stress-responsive AmgRS two-component system

Exposure of P. aeruginosa to the aminoglycoside (AG) paromomycin (PAR) induced expression of the PA3720-armR locus and the mexAB-oprM multidrug efflux operon that AmgR controls, although PAR induction of mexAB-oprM was independent of armR. Multiple AGs promoted mexAB-oprM expression and this was los...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fruci, Michael, Poole, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173428/
https://ncbi.nlm.nih.gov/pubmed/30289929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205036
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