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Antibiotic Inducibility of the mexXY Multidrug Efflux Operon of Pseudomonas aeruginosa: Involvement of the MexZ Anti-Repressor ArmZ

Expression of the mexXY multidrug efflux operon in wild type Pseudomonas aeruginosa is substantially enhanced by the ribosome-targeting antimicrobial spectinomycin (18-fold) and this is wholly dependent upon the product of the PA5471 gene. In a mutant strain lacking the mexZ gene encoding a represso...

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Main Authors: Hay, Thomas, Fraud, Sebastien, Lau, Calvin Ho-Fung, Gilmour, Christie, Poole, Keith
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575510/
https://ncbi.nlm.nih.gov/pubmed/23441219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056858
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