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Oxidative Stress Induction of the MexXY Multidrug Efflux Genes and Promotion of Aminoglycoside Resistance Development in Pseudomonas aeruginosa

Exposure to reactive oxygen species (ROS) (e.g., peroxide) was shown to induce expression of the PA5471 gene, which was previously shown to be required for antimicrobial induction of the MexXY components of the MexXY-OprM multidrug efflux system and aminoglycoside resistance determinant in Pseudomon...

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Detalhes bibliográficos
Main Authors: Fraud, Sebastien, Poole, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067074/
https://ncbi.nlm.nih.gov/pubmed/21173187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01495-10
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