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Oxidative Stress Induction of the MexXY Multidrug Efflux Genes and Promotion of Aminoglycoside Resistance Development in Pseudomonas aeruginosa

Exposure to reactive oxygen species (ROS) (e.g., peroxide) was shown to induce expression of the PA5471 gene, which was previously shown to be required for antimicrobial induction of the MexXY components of the MexXY-OprM multidrug efflux system and aminoglycoside resistance determinant in Pseudomon...

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Autores principales: Fraud, Sebastien, Poole, Keith
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067074/
https://ncbi.nlm.nih.gov/pubmed/21173187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01495-10
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